1 – The PACT (Platelet & Advanced Cell Therapies) Forum: fostering translational research, transdisciplinarity and international collaboration in tissue engineering and regenerative medicine.
Gilberto Sammartino, Marco Del Corso, Lidia M. Wisniewska, Tomasz Bielecki, Isabel Andia, Nelson R. Pinto, Chang-Qing Zhang, De-Rong Zou, and David M. Dohan Ehrenfest.
POSEIDO, Volume 2, Issue 2, June 2014, Pages 105-115
The PACT (Platelet & Advanced Cell therapies) Forum Civitatis of the POSEIDO was created to offer a multidisciplinary platform of research, publication, debates and eventually consensus for researchers in the fields of Tissue Engineering and Regenerative Medicine (TERM). In this review, the issues, endeavors and perspectives of this considerable research field are discussed and illustrated, particularly (but not only) through the example of the history, failures and success of probably the oldest method developed in regenerative medicine, the topical use of autologous platelet concentrates (commonly known as Platelet- Rich Plasma – PRP or Platelet-Rich Fibrin – PRF). The History of this domain illustrates very well that the greatest enemy of knowledge is not ignorance; it is the illusion of knowledge. Fighting against illusions in Sciences is a very complex and tricky task, requiring continuing efforts and time. This PACT for a transdisciplinary, translational and international approach in regenerative medicine is an important step in this endeavor.
Keywords: Blood platelet, fibrin, growth factors, regenerative medicine, tissue engineering.